Mitochondria, our evolutionary internal Master

Mitochondria, our evolutionary internal Master
Mitochondria, our evolutionary internal Master

• Mitochondria, our evolutionary internal Master

Dr. Sameh S. Ali, M.S., Ph.D., Head of Tumor Biology Research Program, 57357 Children's Cancer Hospital, Cairo, Egypt.

Mitochondria are cellular organelles with a plethora of roles in cell biology including bioenergetics, signaling, stress response, immune response, and cell death and survival. Mitochondria are implicated in the evolution of complex life forms, the evolution of sexual reproduction, and aging. Many neurodegenerative, cardiovascular, cancer, and psychological disorders are known to involve mitochondrial dysfunction and deregulated levels of reactive oxygen species. Aging is associated with a sustained increase in superoxide radical levels, which is associated with a progressive decline in cognitive function and increased prevalence of neurodegeneration. Mitochondria were identified as one source of oxidant production in brain during aging, but several recent studies suggest that an alternative, extra-mitochondrial source of superoxide may also be important to aging-associated pathologic phenotype. In this presentation I will briefly introduce current theories on the origin of cellular mitochondria and their potential role in the evolution of complex aerobic life. I will also introduce roles of mitochondria in cancer and aging.

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Bio Team Egypt
We are Egyptian activists in the field of Biotechnology and Entrepreneurship awareness. Researchers, engineers and undergrad students from divers Egyptian universities and institutions. One target has collected us, is to create an Egyptian scientific community which is specialized into Biotechnology.
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